This includes damage to the cartilage which cushions the joints. However, men and women who are active could be at risk of over-use injuries in this decade, says Dr Mark Hamer, an exercise physiologist at University College London. 'I see an increasing number of pregnancy-related back pain problems from women who have lived sedentary lives,' warns physiotherapist Sammy Margo. For many women, this decade is dominated by pregnancy and young motherhood, and hormonal changes can throw up problems.